is nexgard plus safe for dogs

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20-03-2025

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Is NexGard Plus Safe for Dogs? A Comprehensive Review

NexGard Plus is a popular broad-spectrum chewable medication for dogs, designed to protect against fleas, ticks, heartworms, and intestinal worms. While widely used and generally considered safe, understanding its potential side effects, precautions, and how it compares to other options is crucial for responsible pet ownership. This article delves into the safety profile of NexGard Plus, examining its ingredients, reported side effects, potential risks, and answering common concerns.

Understanding NexGard Plus's Ingredients and Mechanism of Action

NexGard Plus contains two active ingredients: afoxolaner and milbemycin oxime. Afoxolaner is a potent insecticide and acaricide, effectively targeting and eliminating fleas and ticks by disrupting their nervous systems. Milbemycin oxime is an antiparasitic drug that combats heartworm larvae and various intestinal worms, including roundworms, hookworms, and whipworms. These ingredients work synergistically to provide comprehensive parasite protection.

The chewable tablet format is designed to make administration easy and palatable for most dogs. The taste is generally appealing, although some dogs may be initially hesitant to consume it. This ease of administration is a significant advantage compared to topical treatments or injectable medications.

Reported Side Effects and Their Frequency

While NexGard Plus is generally well-tolerated, like any medication, it can cause side effects in some dogs. The most commonly reported side effects are generally mild and transient:

• Gastrointestinal Issues: These are the most frequently reported side effects and include vomiting, diarrhea, loss of appetite, and increased salivation. The severity and duration of these symptoms vary widely, with most resolving spontaneously within 24-48 hours.
• Neurological Signs: Less frequently, some dogs may experience neurological symptoms such as lethargy, tremors, ataxia (loss of coordination), or seizures. These are more concerning and require immediate veterinary attention.
• Skin Reactions: Although rare, allergic skin reactions, such as itching, redness, or swelling, are possible.
• Other Side Effects: Other less common side effects include changes in urination or defecation, increased thirst, and behavioral changes.

It's important to note that the frequency of these side effects is generally low. Many studies have shown NexGard Plus to have a favorable safety profile, with most dogs experiencing no adverse effects. However, individual sensitivities vary, and the risk of side effects increases with the dosage and frequency of administration.

Precautions and Contraindications

Before administering NexGard Plus, it is essential to consult with a veterinarian. Certain precautions and contraindications must be considered:

• Pre-existing Conditions: Dogs with a history of seizures or other neurological disorders are at a slightly increased risk of adverse events. Similarly, dogs with liver or kidney disease should be carefully monitored.
• Puppy and Senior Dog Use: While NexGard Plus is approved for use in puppies over 8 weeks old, caution is advised in very young or very old dogs. The veterinarian may recommend alternative treatments.
• Drug Interactions: NexGard Plus can interact with other medications, particularly those affecting the liver or nervous system. Inform your veterinarian about all medications your dog is currently taking.
• Pregnancy and Lactation: The safety of NexGard Plus in pregnant or lactating dogs has not been fully established. Consult your veterinarian before using it during these periods.

Comparing NexGard Plus to Other Parasite Prevention Options

NexGard Plus is just one of many available options for parasite protection in dogs. Other popular choices include:

• Bravecto: A chewable tablet that offers longer-lasting protection (up to 12 weeks) against fleas and ticks.
• Simparica Trio: A chewable tablet protecting against fleas, ticks, heartworms, and intestinal worms, similar to NexGard Plus.
• Revolution: A topical medication providing protection against fleas, ticks, heartworms, and ear mites.
• Frontline Plus: A topical medication primarily effective against fleas and ticks.

The choice of the best parasite preventative depends on several factors, including your dog's individual needs, your budget, and the prevalence of specific parasites in your region. Your veterinarian can help you weigh the pros and cons of each option and choose the most appropriate one for your dog.

Monitoring Your Dog After Administering NexGard Plus

After giving your dog NexGard Plus, monitor them closely for any unusual signs or symptoms. If your dog experiences any side effects, particularly those that are severe or persistent, contact your veterinarian immediately. Early intervention can help prevent complications.

Addressing Common Concerns and Misconceptions

Several common misconceptions surround the safety of NexGard Plus:

• NexGard Plus causes cancer: There is no scientific evidence linking NexGard Plus to an increased risk of cancer in dogs.
• NexGard Plus is too strong: While it is a potent medication, the dosage is carefully calculated to be effective while minimizing the risk of side effects.
• My dog had a bad reaction, so it's unsafe for all dogs: Individual sensitivities vary. A negative experience in one dog doesn't necessarily mean the medication is unsafe for all dogs.

Conclusion

NexGard Plus is a widely used and generally safe medication for protecting dogs against a range of parasites. While the potential for side effects exists, they are generally mild and infrequent. However, responsible pet ownership requires careful consideration of the potential risks, precautions, and alternative options. Open communication with your veterinarian is crucial for determining whether NexGard Plus is the right choice for your dog and for monitoring their health after administration. Regular veterinary check-ups are essential for early detection of any potential problems and ensuring your dog receives optimal care. Remember that this information is for educational purposes only and should not be considered a substitute for professional veterinary advice. Always consult your veterinarian before starting any medication for your pet.